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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5339ed69bbccbfda2cb040c6c2f17dd5e7b5ed356bd0be7128f29f9636ad660d' 
  AND token = 'oj+ElcW0tnwhoZsln5/y1UxWhhLgh20ij/ASX2DS+IQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}