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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80cad5a38d3fd948ac03e41b74d4a8c88b982dabe4c791015b78008a2029e788' 
  AND token = 'qfHk9+lXGefLOJk0o1sQTga2bg1Pqes9GoqabfB+nlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}