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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e845604a4b9e7badec17d9bc593baef3ef23093ce22f3144999c4007ffbde686' 
  AND token = 'ewNV43k3laMzkT592osJ3j6laNRMEk7DIt831WI8ZWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}