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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f51272eb2fc3d0f4ae81f63ad47c56fe172b1dc6dbb110eee1a79c45997682f' 
  AND token = 'FSDI8ta1hfRw+UheG4MVnCIhM2zTtd5fsu2RVxCMXq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}