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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a1086e16b6bf863b9d191070ea5486f1eed3780cba7d02b0c0e3f17115adfe2' 
  AND token = '7OpRypHOr577Znwf3ODbrPY6XvDnaVMNjuSzDk2K3BA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}