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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'feaa310dcea2035d196b7d3d9ac6a1f5698c330d051defa07e1a750109bcfb12' 
  AND token = 'e5HY719DqdIbhc4BlhebgPPu54EMIWs1cRKrCDTWuzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}