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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19f4c0fde718661c05ce524166e81e60db44c25f0c85e4471dffde791e851621' 
  AND token = 'fIicHtZy4Wj6gYbASDvfGuwet16hJXv3zbyHrYjQxho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}