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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1999ce45f48567b2005a964b6cc90f39eccc54bb9c8bdb6dc43f8d55b21c58e4' 
  AND token = '2IIS41RNA5Xd0PJY7bheX1j2EwbCumt3jCaCDzMARZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}