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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc0a33501b250892c10ea5ad38cdb9d0ff23821d17d927f19d5ce6ae521bc805' 
  AND token = 'HyxjFDjJec4aSC3JRxvUDMzslE9dDIMpAAhhFd5+el0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}