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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ff9e87b57d56249df1df46c704f6c3c8c0a45251467330f8c275098fcefd3c8' 
  AND token = 'hpA0UrrUQvn24p9QCyGluRnORx5Sqm5RNM9mw4VUPAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}