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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8d9efd3200b80d5b1765f44b220168e3db555c7eeb2cfc1bd7bc4c0ae7fe92f' 
  AND token = 'u4FrUDC/gG8r4VRjALQ8F6ZQTmCfBj82aBWV4TsYAcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}