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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c21cb0ca4b23213d236ec6296089a527630b24ea671f7c610b9f7628c89bc97' 
  AND token = 'YEPEJEGt6LYIkJuw8QJmf0ZK3+sxxf/g1Ne734iKdzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}