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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae951c6b097a6765f0a481a8d204fa6b06bbbb3036cffddee507edb38a401c50' 
  AND token = 'yL9R1a1bJbX/0+88eMzRayTUTllkkVk7xkD8vjpguXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}