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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f401ce5afa41bc0c8c855d1c9c564f7cd90895a2c18a3eae8b86019910b44365' 
  AND token = 'Na45AHLu/tOe9nQFeORdo+kEsVO9sJSX+GUai4DyXLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}