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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd18a08e1960e00990418656f5fb2438be12bb27f8e80ecdf74e24a0bc3749a8b' 
  AND token = 'ntWipL2H0c1N7otzBUbZR4aZe4vB0f0zweYorhJB+Os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}