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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22fdf5bc77700271738de55ea5df0bc896a442e0f29d28ed2d6d9ee0e7f102a1' 
  AND token = 'vzz4+nrmcOsHEMQtEGgbHgxwJdBln0kF4kB/Y70sV7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}