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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '249e36ad41fd6394046f05061399c57444c56376e920257f63fc4ef37df3ddb7' 
  AND token = 'CMmo5Xa3UIlRXdONuq+t2n3Zxw/Tr0sN2kAMWLaLAtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}