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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70561f8ab5007a7a0e510d57249481dca92fdd5fe9c1cda1d46467ea0164b137' 
  AND token = 'PX9eRZFR8e3grz1GNI9pTV5bRITnmIxirrBus2XWo2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}