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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75892697c9d6817b61e6b9959691441cc1886ffe6fbd1cfe62886cf3c7309217' 
  AND token = 'k0yL/AhcnE3ELPT8ey2Y2OcV+0EnO9WHMeIzjmm0lv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}