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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdac887b953b1327483123af6f230d949e976da2e83170bb811be39fc9b50f22' 
  AND token = 'CONk6VQthcAjz9Fm9JQK3FwWXp9JbAAeERPwp9KUbNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}