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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c38b6d05861fb298e6b829db8866067cb53b74691e04489085a0139959e5188' 
  AND token = 'MiJV/V3yCHI1Ilps+AGya6gCFmP30a8cEDfTrkyaLQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}