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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c8c5866076a864af833e8d26474db15ea25ec721f9d5e79fb6c24c1c5485e48' 
  AND token = 'T8j76PwM11BERmpywPTrQtSXsa5v84Lx+316j8/71yE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}