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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4372c46bf7d10603e94f05c92fb89bc8d1e9449afe1cd756f1f744caa7cb1370' 
  AND token = 'D9bh94lqhCImqAk1h0AA7arv4oBUNUd5hf1u3N4gZt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}