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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2da25e9a26d02180268f1a9dd410c23203d754c5ca442cd5157cca988eee13ed' 
  AND token = 'A4AYVSQQ4CrYI66WHyZR/CdhLLjrUQc940hSmvhziMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}