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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecb399961415fcb0feabf0f47b6ddd21ba83a294bd57d82983504d80e9c63672' 
  AND token = 'zxoRanme7KE2P90YjXBPIL1oD468MZVbL4LMdSGgIKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}