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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '760e552bd77cf84abd00d30cf8d3070da71e4b586d6a11b06e16df6efa9a645b' 
  AND token = 'fDkFNaK6A071HXtVMmxTvHKkaVrSWQi8rCpzN47GRnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}