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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5277c9e485e8fb2f492ba5ce0a58134ff9c9b2e5a50344b33ca5a2d5032954a2' 
  AND token = 'zitHklAn4DUyFdMb5esekLZdgUMTN1yiqZjn9wDMAns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}