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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9a5622158a512a3c54a914f2d8f8dbbc28811466882d129b6944b623f4f0d5' 
  AND token = '56l0d3c4IeLZcnLCZpWoWhOkiaR0yVzL87TRdfcOfOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}