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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1c4f26c2fd5cbb9a47ee4e2e277a14397ce4d3712bb1c82b86cff071ff58d2b' 
  AND token = 'r5skWfchoSYgWNwHZoHoeYsLcGYYSMlbe0RnkCND6U8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}