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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '661913dcb9541e65736e6fe009dd9ac966d6fa8f3bdfcfacd6e6401398cd43a6' 
  AND token = 'SHTrsYRfutuDf8L5m9ZabXPQ+inW00I6bqysQ6fy8co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}