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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd34240a2273bf00d140eb48426e08c6a166d0b4782517d87b5c021c5a2b2223' 
  AND token = 'eszH9+3G57lXNCKdmcmfOrAw5ykA6jo7z6sipfMsqDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}