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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5467297f7848f0d0d2abecba584e4950df0abfeb2cf8cb1de33fde44d0a9c7b9' 
  AND token = '0+TYmX2g+KoXdy7gbPNHQzH3XjLKSnrDusTQ+oLFfrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}