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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4e09327815cbd63d6f040f52420c955adf50051e511ae058e320502e8b30ecd' 
  AND token = 'GZoi/2qGOWbVlx0nl0I21c0NGtHwTmCNMgjyidYlxsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}