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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7568863b421ef5ae83d2a7707ac38e0c93662000ed27a2e7f50047da7e4e3e60' 
  AND token = 'fUKxXZCcO95EI8HfiNFOIoAS7xzByOhukUe43G2v65I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}