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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4b2cedbf9a22932a6e068d3d6ccfd8a6e9a49e2526bd4252eded921c8de50d' 
  AND token = 'ezX2JV0IbTL81bQ1foGqn1AMSLF/6+ib4fCvO9oofFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}