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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f444308095a4f16b297391060b48eda0eecdb256999d8606cf6ab64bce5db093' 
  AND token = 'vwO80m22Kt6hXuu2wn3Wjs5/yiCKUmyAj38b+TBD5bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}