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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02ce65af3cc026eeb6e66f616ad047da72aed34619fbc122bc6de533ca9e61f5' 
  AND token = 'Zdr8mGMKLyjN2VZUrXtiHgacYOPB4mZ4aWEa66YdFPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}