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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c3c7a3344d7a0bdd3e161b8e71db099a73cee95b0edf0f113f32dc558a307e' 
  AND token = '2AiCXbTVJ9bRsigcEjfnh6lL+jNbv1/aQ5iHj9sIrCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}