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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e2b945e18ee6642f7d983e8ee00fe24d63d5b5ddc085d618bb5c1e33033d5ad' 
  AND token = 'JtVHVecC8Ha0Rj7CpYnbkCsw1wq3Z5FoKSdxJQNlyMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}