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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95352a4ac3965b68d00481f19f1d86eb2f852f83f7489ca18e95d1cbb37bb7cc' 
  AND token = 'fzVVdolPn0lK+KabkHyffWnXhoDNxLzKy71EbuvzLgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}