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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7acd2eeeda9fdbd2b2e4d0945cbff7ae2c209ddaae8fbc12a54599058c85c07b' 
  AND token = 'pxubjyGGvd9I2aMEkQqU/0B4hU//9yNwzOTKoXBEXvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}