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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4c2aaf994b9ba18080006e1451e0465c6eda5f150f2c0431e7dedd68b1bb233' 
  AND token = 'tc+96sw1Aw3hwBc70NJ52pjvWli+ANAwN5CKJfrYjd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}