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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ba7d05061eb08c64003418464536c87c2758815bec8be9cc48d74e7b3d7d33b' 
  AND token = 'NDiMV0Cwm0jjPJAUrwrTM1IpCJGuGUB+wsfMyRcCQ2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}