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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0d334b8e09818838437a2d71d19e9c7f48534b6f0a25ed5688756da6dcc7d9' 
  AND token = 'UX3pHoA/2mTXRHZs3f9aX/O8L5D2pDSFEnFIRRHI7yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}