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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e6837f4a46928ce87113823245f0aba8600b475b84ecd3179f14a4642520f1' 
  AND token = 'e1wBN30AizdICmsIisZj1tM5pgyjNcwM6MYLAGXs918=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}