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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f645d75b50eb2a31d17af4fa71bf231a8a327adf503f2c7a5dba6c61c344f97' 
  AND token = 'oK/OB/PYT2Wuo01KVt1MpeXX5SwjO5VH2zzvvdg7xyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}