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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f03ef2d6728977b569c8a187dbd06933059345a3e9376989da35d5e7061275f5' 
  AND token = 'Wu/aSNy5NCbOhn0wEFajx526gCkEsJTYX+UMylQ9ib8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}