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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65297e38cfd554a4999037ebe590f82711bb3c94250baee0f97e40b4b5268b85' 
  AND token = 'G5ny+c9bG3k9lDbAp+TrcWF076wB87DzJnUKcZhi5L4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}