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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ecdb0ee95b00cebb6221809446cd80a2f63957abaccec386c87ab293be24bb5' 
  AND token = 'qPjiLutfSZO9uRId1SI9GCV43f5eV9Gtf9XzME0j6iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}