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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a34b4621edaa7cb8584cc3fffb731bfdab586b9f29dd587480799d790cff1f2' 
  AND token = 'PbT2hbD9w/Y72+AUPmZtISP0J1syNpsuhAg1IEPUtaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}